Universal in vitro antifungal resistance of genetic clades of the Fusarium solani species complex

Antimicrob Agents Chemother. 2007 Apr;51(4):1500-3. doi: 10.1128/AAC.01618-06. Epub 2007 Jan 12.

Abstract

Eleven antifungal drugs were tested against representative isolates of the four phylogenetic clades of the Fusarium solani species complex obtained in a multilocus sequence analysis. They all showed very poor activity, with no differences among the clades. Amphotericin B was the most active drug.

MeSH terms

  • Amphotericin B / pharmacology*
  • Antifungal Agents / pharmacology*
  • Drug Resistance, Fungal / genetics*
  • Drug Resistance, Fungal / physiology
  • Fusarium / drug effects*
  • Fusarium / growth & development
  • Fusarium / isolation & purification
  • Microbial Sensitivity Tests
  • Phylogeny
  • Species Specificity

Substances

  • Antifungal Agents
  • Amphotericin B