Iron in red meat-friend or foe

Meat Sci. 2017 Jan:123:157-165. doi: 10.1016/j.meatsci.2016.09.012. Epub 2016 Oct 2.

Abstract

In developed countries, due to high content and bioavailability, red and processed meats are the main sources of iron in the diet. Adequate intake of this nutrient is essential for the proper development and functioning of the human body, and its deficiencies are associated mainly with the occurrence of anemia, which is one of the most widespread nutritional problems in the world. However, excessive intake of iron can be detrimental to health. Studies have shown that high consumption of red meat and its products, and thereby iron, particularly in the form of heme, increases the risk of non-communicable diseases, including cancers, type II diabetes and cardiovascular disease. Due to the high nutritional value, the presence of red meat in the diet is preferable, but according to World Cancer Research Fund International its consumption should not exceed 500g per week. Furthermore, there are several potential ways to suppress the toxic effects of heme iron in the diet.

Keywords: Cancers; Cardiovascular diseases; Diabetes; Heme; Iron; Red meat.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Availability
  • Body Composition
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / epidemiology
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diet
  • Disease Models, Animal
  • Humans
  • Iron, Dietary / administration & dosage
  • Iron, Dietary / adverse effects*
  • Iron, Dietary / pharmacokinetics
  • Meta-Analysis as Topic
  • Neoplasms / blood
  • Neoplasms / epidemiology
  • Nutritional Requirements
  • Red Meat / analysis*
  • Risk Factors

Substances

  • Iron, Dietary