Abstract
The intestinal epithelium of the neonatal rat is a model system for the study of receptor-mediated endocytosis in which large amounts of IgG are transferred intact across polarized cells. This review summarizes the ultrastructural pathway followed by IgG during cellular transit and several important properties of the membrane receptor that recognizes the IgG.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Biological Transport
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Electrophoresis, Polyacrylamide Gel
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Endocytosis
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Epithelium / ultrastructure
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Hydrogen-Ion Concentration
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Immunoglobulin G / metabolism*
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Intestine, Small / cytology
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Microscopy, Electron
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Microscopy, Electron, Scanning
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Rats
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Receptors, IgG
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Receptors, Immunologic / metabolism*
Substances
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Immunoglobulin G
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Receptors, IgG
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Receptors, Immunologic