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Year | Number of Results |
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2003 | 1 |
2005 | 1 |
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2016 | 1 |
2018 | 1 |
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Page 1
Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4.
Bioorg Med Chem Lett. 2015 Dec 1;25(23):5546-50. doi: 10.1016/j.bmcl.2015.10.060. Epub 2015 Oct 23.
Bioorg Med Chem Lett. 2015.
PMID: 26526214
Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385).
Wehn PM, Rizzi JP, Dixon DD, Grina JA, Schlachter ST, Wang B, Xu R, Yang H, Du X, Han G, Wang K, Cao Z, Cheng T, Czerwinski RM, Goggin BS, Huang H, Halfmann MM, Maddie MA, Morton EL, Olive SR, Tan H, Xie S, Wong T, Josey JA, Wallace EM.
Wehn PM, et al. Among authors: cao z.
J Med Chem. 2018 Nov 8;61(21):9691-9721. doi: 10.1021/acs.jmedchem.8b01196. Epub 2018 Oct 18.
J Med Chem. 2018.
PMID: 30289716
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A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma.
Wallace EM, Rizzi JP, Han G, Wehn PM, Cao Z, Du X, Cheng T, Czerwinski RM, Dixon DD, Goggin BS, Grina JA, Halfmann MM, Maddie MA, Olive SR, Schlachter ST, Tan H, Wang B, Wang K, Xie S, Xu R, Yang H, Josey JA.
Wallace EM, et al. Among authors: cao z.
Cancer Res. 2016 Sep 15;76(18):5491-500. doi: 10.1158/0008-5472.CAN-16-0473. Epub 2016 Sep 6.
Cancer Res. 2016.
PMID: 27635045
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Structure of the nuclear factor κB-inducing kinase (NIK) kinase domain reveals a constitutively active conformation.
Liu J, Sudom A, Min X, Cao Z, Gao X, Ayres M, Lee F, Cao P, Johnstone S, Plotnikova O, Walker N, Chen G, Wang Z.
Liu J, et al. Among authors: cao z.
J Biol Chem. 2012 Aug 10;287(33):27326-34. doi: 10.1074/jbc.M112.366658. Epub 2012 Jun 20.
J Biol Chem. 2012.
PMID: 22718757
Free PMC article.
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Accessory protein-like is essential for IL-18-mediated signaling.
Cheung H, Chen NJ, Cao Z, Ono N, Ohashi PS, Yeh WC.
Cheung H, et al. Among authors: cao z.
J Immunol. 2005 May 1;174(9):5351-7. doi: 10.4049/jimmunol.174.9.5351.
J Immunol. 2005.
PMID: 15843532
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Development of a high throughput time-resolved fluorescence resonance energy transfer assay for TRAF6 ubiquitin polymerization.
Hong CA, Swearingen E, Mallari R, Gao X, Cao Z, North A, Young SW, Huang SG.
Hong CA, et al. Among authors: cao z.
Assay Drug Dev Technol. 2003 Feb;1(1 Pt 2):175-80. doi: 10.1089/154065803321537890.
Assay Drug Dev Technol. 2003.
PMID: 15090144
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Pillars article: MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 1997. 7: 837-847.
Wesche H, Henzel WJ, Shillinglaw W, Li S, Cao Z.
Wesche H, et al. Among authors: cao z.
J Immunol. 2013 Jan 1;190(1):5-15.
J Immunol. 2013.
PMID: 23264669
No abstract available.
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