Name	Known for
Iain Armitage Sheldon Cooper Sheldon Cooper See fewer	Young Sheldon (2017)
Zoe Perry Mary Cooper Mary Cooper See fewer	Young Sheldon (2017)
Lance Barber George Cooper Sr. George Cooper Sr. See fewer	Gangster Squad (2013)
Montana Jordan Georgie Cooper Georgie Cooper See fewer	Young Sheldon (2017)
Raegan Revord Missy Cooper Missy Cooper See fewer	Young Sheldon (2017)
Emily Osment Mandy McAllister Mandy McAllister See fewer	Hannah Montana: The Movie (2009)
Annie Potts Connie 'Meemaw' Tucker Connie 'Meemaw' Tucker See fewer	Ghostbusters (1984)
Jim Parsons Sheldon Cooper (voice) Sheldon Cooper (voice) See fewer	The Big Bang Theory (2007)
Ed Begley Jr. Dr. Linkletter Dr. Linkletter See fewer	A Mighty Wind (2003)
Wendie Malick President Hagemeyer President Hagemeyer See fewer	The American President (1995)
Rachel Bay Jones Audrey McAllister Audrey McAllister See fewer	Georgie and Mandy's First Marriage (2024)
Eddie Shin Mr. Stevens Mr. Stevens See fewer	Alexa & Katie (2018)
Troy Blendell Phil Lambert Phil Lambert See fewer	Bosch: Legacy (2022)
Melody Butiu Mrs. Jameson Mrs. Jameson See fewer	Easter Sunday (2022)
Bob Glouberman Mr. Jensen Mr. Jensen See fewer	Ultimate Spider-Man (2005)
Reece Rios Mr. Beaudry Mr. Beaudry See fewer	The Walking Dead: World Beyond (2020)
Wallace Shawn Dr. John Sturgis Dr. John Sturgis See fewer	My Dinner with Andre (1981)
Reagan To Mei-Tung (archive footage) (uncredited) Mei-Tung (archive footage) (uncredited) See fewer	Young Sheldon (2017)