- Underwent brain surgery in 2012 to treat a pituitary tumour.
- Underwent surgery to repair a retinal detachment aged 9, following an accident in a swimming pool.
- He uses his maternal grandfather's name as his stage name because he found another actor was using his birth name (Stephen Thorpe).
- Became a father for the first time at age 35 when now estranged wife Claire Foy gave birth to their daughter Ivy Rose Moore (b. March 2015).
- He and his wife, Claire Foy, have both played a King and Queen of the same family. Stephen played King Edward VIII in Wallis & Edward (2005) and Claire played Queen Elizabeth II (Edward's niece) in The Crown (2016).
- Was nominated for 2006 Drama Desk Award - Outstanding Featured Actor in a Play for his role as Irwin in The History Boys.
- He is the son of a telecommunications engineer (father) and hospital dietitian-turned-art therapist (mother). He has an older brother who works as an engineer.
- Graduated from Guildhall School of Music and Drama in 1999. He was awarded the Gold Medal.
- Although born in London he was brought up in Hertfordshire and educated at Berkhamsted School.
- At one time he lived in the East Village of Manhattan with his Italian girlfriend Ra, who was a graduate student at Columbia University.
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