In the opening credits, the title is misspelled "The Trouble with Spys"
The Russian spymaster Novikov's name is misspelled on his nameplate. It uses a letter for 'i' that only appears at the end of words or in vowel blends, never on its own.
At approximately 8:45 in the movie the Hotel Owner calls the agent 'Donald' (Sutherland's actual name) not the character's name 'ARNOLD'