Donald Pleasence was very vocal about his dissatisfaction with the story and with the way director Dominique Othenin - Girard was trying to get him to play Dr Loomis as totally heavy and overbearing. Pleasence also felt that the box office success and the shock ending of Halloween 4: The Return of Michael Myers (1988) was not being capitalised upon.
After filming for two weeks, Donald Pleasence gave his much bigger trailer to Danielle Harris once he left set. Harris's mother had been complaining about the small size of her daughter's trailer and Pleasence decided that she should have his.
Despite the subtitle "The Revenge of Michael Myers" which appears on all movie covers and posters, it does not appear in the actual film. It only says "Halloween 5" in the opening credits.
The scene where Michael Myers drives a car while wearing a different kind of mask was initially scripted to have him wear a Ronald Reagan mask. However, the idea of a Reagan mask was soon rejected in order to keep the film devoid of any political subtexts.
Donald Pleasence had disagreements with Akkad and Othenin-Girard citing that Jamie should have been portrayed as "all evil" after stabbing her stepmother, Akkad disagreed thinking that fans wanted to see more of The Shape. In an interview, Danielle Harris explained what she thought of the idea: "The way Halloween 4 ended I thought I was going to be the Killer, I thought it would have been fun to come back as the Killer or Michael's sidekick. Scary, but fun".