Maple syrup urine disease metabolites induce apoptosis in neural cells without cytochrome c release or changes in mitochondrial membrane potential

Biochem Soc Trans. 1998 Nov;26(4):S341. doi: 10.1042/bst026s341.

Authors

P Jouvet¹, P Rustin, U Felderhoff, J Pocock, U Joashi, N D Mazarakis, C Sarraf, A D Edwards, H Mehmet

Affiliation

¹ Weston Laboratory, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK.

PMID: 10047855
DOI: 10.1042/bst026s341

No abstract available

MeSH terms

Apoptosis*
Cytochrome c Group / metabolism*
Humans
Maple Syrup Urine Disease / enzymology
Maple Syrup Urine Disease / metabolism*
Maple Syrup Urine Disease / pathology
Membrane Potentials*
Mitochondria / enzymology
Mitochondria / physiology*
Neurons / pathology*

Substances

Cytochrome c Group