Abstract
The germ-free pig model is shown to be useful for studying salmonellosis. The immune status of germ-free and infected gnotobiotic piglets is described. The regulatory role of cytokine is discussed and compared with our experimental findings.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Bacterial / blood
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B-Lymphocytes / microbiology
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Disease Models, Animal*
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Immunoglobulin A / blood
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Immunoglobulin G / blood
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Immunoglobulin M / blood
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Interferon-gamma / blood
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Salmonella Infections, Animal / immunology*
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Salmonella Infections, Animal / microbiology*
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Salmonella typhimurium / immunology*
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Specific Pathogen-Free Organisms
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Swine*
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Tumor Necrosis Factor-alpha / metabolism
Substances
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Antibodies, Bacterial
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Immunoglobulin A
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Immunoglobulin G
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Immunoglobulin M
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Tumor Necrosis Factor-alpha
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Interferon-gamma