Spontaneous remission of anemia associated with a myelodysplastic syndrome with disease evolution into a myeloproliferative state

A Tefferi; D J Inwards; J D Hoyer

doi:10.1159/000040921

Spontaneous remission of anemia associated with a myelodysplastic syndrome with disease evolution into a myeloproliferative state

Acta Haematol. 1999 Mar;101(1):50-2. doi: 10.1159/000040921.

Authors

A Tefferi¹, D J Inwards, J D Hoyer

Affiliation

¹ Division of Hematology and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn. 55905, USA.

PMID: 10085439
DOI: 10.1159/000040921

Abstract

A red cell transfusion-dependent patient with a myelodysplastic syndrome had progression into a myeloproliferative state with thrombocytosis. At the same time, the patient became transfusion independent, and a subsequent bone marrow examination revealed a previously undetected loss of chromosome 7. The patient remains well with control of thrombocytosis by anagrelide therapy.

Publication types

Case Reports

MeSH terms

Anemia / complications*
Anemia / physiopathology
Chromosomes, Human, Pair 7
Disease Progression
Female
Humans
Middle Aged
Myelodysplastic Syndromes / complications*
Myelodysplastic Syndromes / genetics
Myelodysplastic Syndromes / physiopathology
Myeloproliferative Disorders / complications*
Myeloproliferative Disorders / genetics
Myeloproliferative Disorders / physiopathology
Remission, Spontaneous
Thrombocytosis / complications*
Thrombocytosis / physiopathology