Seed versus soil: the importance of the target cell for transgenic models of human leukemias

Blood. 1999 Apr 1;93(7):2143-8.

Authors

P Westervelt¹, T J Ley

Affiliation

¹ Division of Bone Marrow Transplantation and Stem Cell Biology, Washington University School of Medicine, St Louis, MO 63110-1093, USA.

PMID: 10090920

No abstract available

Publication types

Review

MeSH terms

Animals
Cell Lineage
Cell Transformation, Neoplastic / genetics*
Gene Expression Regulation, Leukemic
Hematopoiesis
Hematopoietic Stem Cells / classification
Hematopoietic Stem Cells / pathology*
Humans
Leukemia, Experimental / genetics*
Leukemia, Experimental / pathology
Mice
Mice, Inbred NOD
Mice, SCID
Mice, Transgenic
Neoplasm Proteins / genetics
Neoplasm Proteins / physiology
Oncogene Proteins, Fusion / genetics
Oncogene Proteins, Fusion / physiology
Oncogenes
Translocation, Genetic

Substances

Neoplasm Proteins
Oncogene Proteins, Fusion
PLZF-RARalpha fusion protein, human
PLZF-RARalpha fusion protein, mouse
promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein