The problems experienced by generalist nurses in providing care to patients who abuse alcohol and other drugs have been acknowledged in the literature. Despite the demonstrated success of educational programs in improving attitudes and enhancing the confidence of nurses in dealing with this clientele, the problem remains. Although large numbers of nurses specialize in the care of patients with drug- and alcohol-related problems, their specific skills have not been well researched. This article reports on a qualitative research project undertaken with 6 nurses currently practicing in a drug and alcohol unit in metropolitan Victoria, Australia. The findings suggest that these nurses are very skilled in their area of practice, and they can potentially provide information and support to nurses from other areas. This liaison role can help minimize the negative experiences frequently encountered by nonspecialist nurses caring for patients with drug- and alcohol-related problems.