Purpose: We recorded multifocal electroretinograms (m-ERGs) in patients with branch retinal artery occlusion (BRAO) and compared the waveform in the area of retinal artery occlusion with that in the normal area, to evaluate the influence of the damage of the inner retina on the m-ERG.
Subjects and methods: Three patients who had normal visual acuity and visual field loss of more than one quadrant due to BRAO were examined. The waveform of first-order and second-order kernel responses of m-ERG in the area of retinal artery occlusion were compared with those of the vertically symmetrical, normally perfused area of the same eye.
Results: Prolongation of latency and decrease of amplitude were noted for the first negative wave (N 1), the first positive wave (P1), and the second negative wave (N2) in the first-order kernel responses in the area of retinal artery occlusion in comparison with the normally perfused area. Second-order kernel responses were not detected in the area of retinal artery occlusion.
Conclusions: The damage to the inner retina affected portions N1, P1, and N2 of the first-order kernel responses, and N2 was the most seriously affected. Second-order kernel responses appear to reflect more strongly the function of the inner retina.