Allogeneic bone marrow transplantation for advanced Waldenstrom's macroglobulinemia

Bone Marrow Transplant. 1999 Apr;23(7):747-9. doi: 10.1038/sj.bmt.1701633.

Abstract

Waldenstrom's disease is a lymphoproliferative disorder that is typically treated with plasmapheresis and/or alkylating agents. In young patients, other lymphoproliferative disorders have been treated with allogeneic transplantation. Two patients with aggressive Waldenstrom's disease, who progressed in spite of multi-agent chemotherapy and autologous stem cell transplantation, in one case, underwent allogeneic transplantation from their HLA-identical donors. Both remain alive with event-free survivals of more than 3, and more than 9 years, respectively. Allogeneic transplantation should be considered for young patients with Waldenstrom's disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Marrow Transplantation*
  • Female
  • Humans
  • Male
  • Transplantation, Homologous
  • Waldenstrom Macroglobulinemia / therapy*