Heteroduplexes may confuse the interpretation of PCR-based molecular tests for the Friedreich ataxia GAA triplet repeat

Hum Mutat. 1999;13(4):328-30. doi: 10.1002/(SICI)1098-1004(1999)13:4<328::AID-HUMU10>3.0.CO;2-J.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blotting, Southern
  • Diagnosis, Differential
  • Friedreich Ataxia / diagnosis
  • Friedreich Ataxia / genetics*
  • Humans
  • Nucleic Acid Heteroduplexes*
  • Polymerase Chain Reaction / methods
  • Reproducibility of Results
  • Trinucleotide Repeat Expansion
  • Trinucleotide Repeats*

Substances

  • Nucleic Acid Heteroduplexes