Isolation of a psychrotrophic Azospirillum sp. and characterization of its extracellular protease

FEMS Microbiol Lett. 1999 May 1;174(1):173-8. doi: 10.1111/j.1574-6968.1999.tb13565.x.

Abstract

A novel psychrotrophic bacterium secreting a protease was isolated from a mountain soil in Korea. On the basis of a 16S rDNA sequence analysis and physiological properties, the isolate was identified as an Azospirillum sp. The protease purified from the culture supernatant was a monomer in its native form with an apparent molecular mass of 48.6 kDa on SDS-PAGE. The protease was active in a broad pH range around 8.5 and at temperatures up to 40 degrees C and stable at temperatures below 30 degrees C for 3 days. The proteolytic activity was inhibited by iodoacetamide and EDTA. The Mg2+ ion did not activate the enzyme much but reversed the inhibition by EDTA, suggesting that the protease belongs to a cysteine protease stabilized by the Mg2+ ion.

MeSH terms

  • Azospirillum / classification
  • Azospirillum / enzymology*
  • Azospirillum / isolation & purification
  • Bacterial Typing Techniques
  • Cold Temperature
  • Endopeptidases / isolation & purification*
  • Molecular Sequence Data
  • RNA, Ribosomal, 16S / genetics
  • Soil Microbiology

Substances

  • RNA, Ribosomal, 16S
  • Endopeptidases

Associated data

  • GENBANK/AF112477