A case of SLE with acute, subacute and chronic cutaneous lesions successfully treated with Dapsone

R Neri; M Mosca; E Bernacchi; S Bombardieri

doi:10.1191/096120399678847713

A case of SLE with acute, subacute and chronic cutaneous lesions successfully treated with Dapsone

Lupus. 1999;8(3):240-3. doi: 10.1191/096120399678847713.

Authors

R Neri¹, M Mosca, E Bernacchi, S Bombardieri

Affiliation

¹ Department of Internal Medicine, University of Pisa, Italy.

PMID: 10342718
DOI: 10.1191/096120399678847713

Abstract

We describe a patient with systemic lupus erythematosus (SLE) who exhibited severe cutaneous involvement characterized by the simultaneous presence of acute, subacute and discoid lesions in association with anti-S1 antibodies. After she failed to respond to chloroquine, medium to low dose steroids, steroid pulses, retinoids and cyclophosphamide, the patient was treated with Dapsone and a dramatic improvement in the cutaneous lesions was seen after only one month.

Publication types

Case Reports

MeSH terms

Acute Disease
Adult
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Chronic Disease
Dapsone / therapeutic use*
Female
Humans
Lupus Erythematosus, Cutaneous / drug therapy*
Lupus Erythematosus, Cutaneous / pathology
Lupus Erythematosus, Discoid / drug therapy
Lupus Erythematosus, Discoid / pathology
Lupus Erythematosus, Systemic / drug therapy*
Lupus Erythematosus, Systemic / pathology

Substances

Anti-Inflammatory Agents, Non-Steroidal
Dapsone