Abstract
Human cytomegalovirus UL25 codes for a structural phosphoprotein of 85 kDa (C. J. Baldick and T. Shenk, J. Virol. 70:6097-6105, 1996; M. C. Battista et al., J. Virol. 73:3800-3809, 1999). In this study we analyzed the intracellular and intraviral localization of pUL25 by confocal and immunoelectron microscopy and found that pUL25 is a component of the viral tegument and the dense body matrix, acquired during the late cytoplasmic phase of virus maturation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line
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Cytomegalovirus / chemistry*
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Cytomegalovirus / ultrastructure
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Fluorescent Antibody Technique, Indirect
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Humans
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Phosphoproteins / analysis
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Phosphoproteins / biosynthesis
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Viral Proteins / analysis*
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Viral Proteins / biosynthesis
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Viral Structural Proteins / analysis*
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Viral Structural Proteins / biosynthesis
Substances
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Phosphoproteins
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UL25 protein, Cytomegalovirus
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Viral Proteins
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Viral Structural Proteins