Abstract
Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Female
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Flaviviridae* / genetics
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Flaviviridae* / isolation & purification
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Hepatitis, Viral, Human / transmission*
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Humans
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Infant
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Infant, Newborn
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Infectious Disease Transmission, Vertical*
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Molecular Sequence Data
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Phylogeny
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Pregnancy
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Pregnancy Complications, Infectious / virology*
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RNA Helicases
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RNA, Viral / analysis
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RNA, Viral / genetics
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Risk Factors
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Serine Endopeptidases
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Tanzania
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Viral Nonstructural Proteins / genetics
Substances
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NS3 protein, flavivirus
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RNA, Viral
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Viral Nonstructural Proteins
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Serine Endopeptidases
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RNA Helicases
Associated data
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GENBANK/AF099442
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GENBANK/AF099443
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GENBANK/AF099444
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GENBANK/AF099445
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GENBANK/AF099446
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GENBANK/AF099447
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GENBANK/AF099448
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GENBANK/AF099449
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GENBANK/AF099450
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GENBANK/AF099451
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GENBANK/AF099452
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GENBANK/AF099453
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GENBANK/AF099454
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GENBANK/AF099455
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GENBANK/AF099456
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GENBANK/AF099457
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GENBANK/AF099458
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GENBANK/AF099459
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GENBANK/AF099460
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GENBANK/AF099461
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GENBANK/AF099462
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GENBANK/AF099463
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GENBANK/AF099464
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GENBANK/AF099465
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GENBANK/AF099466
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GENBANK/AF099467
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GENBANK/AF099468
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GENBANK/AF099469
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GENBANK/AF099470
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GENBANK/AF099471