Abstract
Chromatographic fractionation of a MeOH extract from the stems of Annona cherimola led to the isolation of a new non-adjacent, bis-THF ring acetogenin (one THF ring being at C-4 and the other at C-16), aromin-A (1) along with the known cytotoxic acetogenin squamocin (2). The structures of these isolates were established by means of mass spectrometry and spectroscopic techniques.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry*
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / toxicity
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Cell Survival / drug effects
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Chromatography, Thin Layer
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Furans / chemistry*
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Furans / isolation & purification
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Furans / toxicity
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Lactones / chemistry*
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Lactones / isolation & purification
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Lactones / toxicity
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Plant Stems
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Plants, Medicinal*
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Furans
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Lactones
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aromin-A