Abstract
A new macrocyclic lactone antibiotic mathemycin B (1) was isolated from the fermentation broth of an Actinomycete sp. culture Y-8620959. The structure of 1 was elucidated by high-resolution MS and interpretation of 2D NMR results. Mathemycin B is active against a variety of phytopathogenic organisms.
MeSH terms
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Actinomycetales / chemistry*
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Antifungal Agents / isolation & purification*
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Antifungal Agents / pharmacology
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Fermentation
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Fungi / drug effects
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Macrolides*
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Microbial Sensitivity Tests
Substances
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Anti-Bacterial Agents
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Antifungal Agents
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Macrolides
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mathemycin B