T-cell lymphoma showing a non-enhancing diffuse white matter lesion with marked brain atrophy

Intern Med. 1999 Jun;38(6):507-11. doi: 10.2169/internalmedicine.38.507.

Abstract

We report an autopsy case of T-cell lymphoma with diffuse white matter infiltration. Cranial magnetic resonance (MR) images showed atrophy of the brain with a diffuse, non-enhancing, T2-high signal intensity lesion in the cerebral white matter. Intra-axial infiltration of T-cell lymphoma should be considered a differential diagnosis in patients with these MRI findings.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Atrophy / metabolism
  • Atrophy / pathology
  • Biomarkers, Tumor / metabolism
  • Brain / metabolism
  • Brain / pathology*
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / metabolism
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Lymphoma, T-Cell / diagnosis*
  • Lymphoma, T-Cell / metabolism
  • Magnetic Resonance Imaging
  • Male
  • Nerve Tissue Proteins / metabolism
  • Thiolester Hydrolases / metabolism
  • Ubiquitin Thiolesterase

Substances

  • Biomarkers, Tumor
  • Nerve Tissue Proteins
  • Thiolester Hydrolases
  • Ubiquitin Thiolesterase