Ventriculostomy is a useful technique for the management of acute hydrocephalus or increased intracranial pressure. The mean rate of ventricular infections is 10%. This risk can be decreased by selecting indications, adherence to aseptic insertion techniques, avoiding CSF leakage, tunneling the catheter, using closed systems and limiting line manipulations. Duration of ventriculostomy drainage remains controversial, as well as systematic change of drain every five days of drainage. The value of local or general prophylactic antibiotic treatment remains to be substantiated.