Functional significance of mild cognitive impairment in elderly patients without a dementia diagnosis

Am J Geriatr Psychiatry. 1999 Summer;7(3):213-20. doi: 10.1097/00019442-199908000-00005.

Abstract

The authors investigated differences in functional ability among three groups of subjects who were not diagnosed with dementia: normal control (NC) subjects (n=35); Clinical Dementia Rating Scale (CDRS) score of 0 (minimal impairment; n=26); and CDRS 0. 5 (questionable dementia; n=42). CDRS 0 and 0. 5 patients reported significantly poorer functioning than NCs in household and other activities, but CDRS 0 and CDRS 0. 5 groups did not differ in self-reported functioning. It is likely that CDRS 0. 5 patients overestimated their functional abilities. Correlations between self- and informant reports of functional status were significantly lower in the CDRS 0. 5 group than in the CDRS 0 group, an important finding for clinical management because patients with questionable dementia may actually be more impaired than they admit. Informants' reports or standardized performance-based assessment should be considered in the clinical evaluation of such patients.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Activities of Daily Living
  • Adult
  • Aged
  • Case-Control Studies
  • Cognition Disorders / diagnosis*
  • Dementia / diagnosis*
  • Female
  • Geriatric Assessment
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Observer Variation
  • Psychiatric Status Rating Scales
  • Self Disclosure