Paratesticular desmoplastic small round cell tumor: case report and review of the literature

J Surg Oncol. 1999 Aug;71(4):269-72. doi: 10.1002/(sici)1096-9098(199908)71:4<269::aid-jso13>3.0.co;2-m.

Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm mainly affecting young males and typically located in the abdomen. Prognosis is generally very poor. We report a rare case of paratesticular DSRCT in a 17-year-old boy, presenting with an isolated left scrotal mass. The patient had an excellent outcome after complete surgical resection of the tumor and adjuvant multi-agent chemotherapy. DSRCT should be included in the differential diagnosis of small round cell tumors of the paratesticular region in adolescents and young adults. Tumor resection and chemotherapy may be beneficial for these patients. Our experience and a review of the literature suggest that DSRCT located in the paratesticular region may have a better prognosis than its more frequent abdominal counterpart.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / surgery*
  • Combined Modality Therapy
  • Dactinomycin / administration & dosage
  • Genital Neoplasms, Male / drug therapy
  • Genital Neoplasms, Male / surgery*
  • Humans
  • Ifosfamide / administration & dosage
  • Male
  • Scrotum*
  • Urologic Surgical Procedures, Male / methods
  • Vincristine / administration & dosage

Substances

  • Dactinomycin
  • Vincristine
  • Ifosfamide

Supplementary concepts

  • IVA protocol