Two cases of nonconvulsive status epilepticus in association with tiagabine therapy

Epilepsia. 1999 Aug;40(8):1159-62. doi: 10.1111/j.1528-1157.1999.tb00835.x.

Abstract

We report two patients with intractable partial seizures who developed generalized nonconvulsive status epilepticus (NCSE) after receiving tiagabine (TGB). Neither had a history of absence seizures or generalized epileptic discharges on prior EEG monitoring. Clinicians need to be aware of a possible association between TGB and NCSE.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use
  • Electroencephalography / statistics & numerical data
  • Epilepsies, Partial / drug therapy*
  • Female
  • Humans
  • Male
  • Nipecotic Acids / adverse effects*
  • Nipecotic Acids / therapeutic use
  • Status Epilepticus / chemically induced*
  • Tiagabine

Substances

  • Anticonvulsants
  • Nipecotic Acids
  • Tiagabine