Abstract
This case report serves to emphasize two important features of metastatic breast carcinoma. First, that tamoxifen-induced flare, although a rare and self-limiting phenomenon, may be fatal and must thus be recognized and treated promptly. Secondly, those patients presenting with hypercalcaemia, as part of tamoxifen-induced tumour flare, invariably have metastatic disease but they may enjoy a durable prognosis if this is confined to the skeleton.
MeSH terms
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Aged
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Antineoplastic Agents, Hormonal / administration & dosage
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Antineoplastic Agents, Hormonal / adverse effects*
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Bone Neoplasms / pathology
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Bone Neoplasms / secondary*
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Breast Neoplasms / drug therapy*
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Breast Neoplasms / pathology
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Female
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Humans
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Hypercalcemia / chemically induced*
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Hypercalcemia / pathology
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Postmenopause
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Prognosis
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Tamoxifen / administration & dosage
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Tamoxifen / adverse effects*
Substances
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Antineoplastic Agents, Hormonal
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Tamoxifen