Botulinum toxoid in the management of gustatory sweating (Frey's syndrome) after superficial parotidectomy

Br J Plast Surg. 1999 Apr;52(3):230-1. doi: 10.1054/bjps.1998.3058.

Abstract

Botulinum toxin has been successfully used to treat Frey's syndrome occurring in a 31-year-old patient following superficial parotidectomy for pleomorphic adenoma. An initial injection of 7.5 U (0.3 ml over 6 cm2 of cheek) resulted in 3 months' resolution of gustatory sweating and flushing and a second injection 12 months' symptomatic improvement. The symptoms recurred after further facial surgery.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoma, Pleomorphic / surgery
  • Adult
  • Botulinum Toxins, Type A / therapeutic use*
  • Female
  • Humans
  • Neuromuscular Agents / therapeutic use*
  • Parotid Neoplasms / surgery
  • Postoperative Complications / therapy*
  • Sweating, Gustatory / etiology
  • Sweating, Gustatory / therapy*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A