In vitro drug-induced cytotoxicity predicts clinical response to high-dose chlorambucil in B-cell chronic lymphocytic leukemia

MeSH terms

• Aged
• Antineoplastic Agents, Alkylating / pharmacology*
• Antineoplastic Agents, Alkylating / therapeutic use
• Cell Survival
• Chlorambucil / pharmacology*
• Chlorambucil / therapeutic use
• Coloring Agents
• Drug Screening Assays, Antitumor
• Female
• Humans
• Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
• Leukemia, Lymphocytic, Chronic, B-Cell / pathology
• Male
• Multivariate Analysis
• Neoplastic Stem Cells / drug effects*
• Remission Induction
• Tetrazolium Salts
• Thiazoles
• Treatment Outcome