Abstract
A new polyisoprenylated phloroglucinol derivative has been isolated from the twigs of Marila laxiflora and characterized on the basis of 1D and 2D NMR spectra. Laxifloranone (1) shows moderate inhibition of the cytopathic effects of in vitro HIV infection.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-HIV Agents / chemistry
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Anti-HIV Agents / isolation & purification*
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Anti-HIV Agents / pharmacology
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Cell Line
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Cytopathogenic Effect, Viral / drug effects
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HIV Infections / drug therapy*
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Humans
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Magnetic Resonance Spectroscopy
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Phloroglucinol / analogs & derivatives*
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Phloroglucinol / chemistry
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Phloroglucinol / isolation & purification
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Phloroglucinol / pharmacology
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Plants, Medicinal / chemistry*
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Spectrometry, Mass, Fast Atom Bombardment
Substances
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Anti-HIV Agents
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laxifloranone
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Phloroglucinol