[Merkel cell carcinoma. Utility of scintigraphy with 111In-DTPA-pentetreotide]

Rev Esp Med Nucl. 1999 Aug;18(4):287-91.
[Article in Spanish]

Abstract

Merkel cell carcinoma (MCC) is an unusual malignant primary skin tumor, having a high incidence of local recurrent, and regional and distant metastasis. Due to its capacity to express somatostatin receptors, it can be detected in vivo with 111In-pentetreotide scintigraphy (Ostreoscan). We present a case of a MCC whose scintigraphy revealed regional metastases of a primary frontal cutaneous tumor that had been removed previously. The results verified a good correlation with clinical, radiological an histopathological findings.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Carcinoma, Merkel Cell / diagnosis
  • Carcinoma, Merkel Cell / diagnostic imaging*
  • Carcinoma, Merkel Cell / pathology
  • Carcinoma, Merkel Cell / secondary*
  • Carcinoma, Small Cell / diagnosis
  • Carcinoma, Squamous Cell / diagnosis
  • Diagnostic Errors
  • Humans
  • Indium Radioisotopes*
  • Lentigo / diagnosis
  • Lymphatic Metastasis / diagnostic imaging
  • Male
  • Neoplasm Invasiveness
  • Neoplasm Proteins / analysis
  • Parotid Neoplasms / diagnostic imaging*
  • Parotid Neoplasms / secondary*
  • Pentetic Acid*
  • Phosphopyruvate Hydratase / analysis
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / diagnostic imaging*
  • Skin Neoplasms / pathology
  • Somatostatin / analogs & derivatives*
  • Tomography, Emission-Computed, Single-Photon*
  • Tomography, X-Ray Computed

Substances

  • Biomarkers, Tumor
  • Indium Radioisotopes
  • Neoplasm Proteins
  • Somatostatin
  • Pentetic Acid
  • Phosphopyruvate Hydratase
  • pentetreotide