Relation between interstitial myocardial collagen and the degree of clinical impairment in Chagas' disease

C Mady; B M Ianni; E Arteaga; G S Montes; E G Caldini; G Andrade; M C Giorgi; P H Saldiva

doi:10.1016/s0002-9149(99)00295-7

Relation between interstitial myocardial collagen and the degree of clinical impairment in Chagas' disease

Am J Cardiol. 1999 Aug 1;84(3):354-6, A9. doi: 10.1016/s0002-9149(99)00295-7.

Authors

C Mady¹, B M Ianni, E Arteaga, G S Montes, E G Caldini, G Andrade, M C Giorgi, P H Saldiva

Affiliation

¹ Heart Institute and Department of Pathology, University of São Paulo Medical School, Brazil. [email protected]

PMID: 10496454
DOI: 10.1016/s0002-9149(99)00295-7

Abstract

Cardiac performance is negatively associated with interstitial collagen in Chagas' cardiomyopathy. The magnitude of dysfunction is related to the degree of collagen, and this association seems to exhibit a threshold above it if definite cardiac deterioration occurs.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Chagas Disease / pathology*
Chagas Disease / physiopathology*
Collagen*
Female
Fibrosis / diagnosis
Heart / diagnostic imaging
Humans
Male
Middle Aged
Myocardium / pathology*
Radionuclide Ventriculography

Substances

Collagen