[Brain 3 D-CT angiography was a useful tool for diagnosis of internal carotid-posterior communicating artery aneurysm: a case of false negative 3 D-MRA]

No To Shinkei. 1999 Sep;51(9):805-8.
[Article in Japanese]

Abstract

A 75-year-old woman with hypertension suddenly developed ptosis in the left eyelid. Neurological examination revealed left oculomotor nerve palsy. Brain T 2-weighted imaging showed abnormal flow void sign in the proximal portion of left middle cerebral artery. Other MRIs, including gadolinium enhancement, were normal. However, brain 3 D-MRA, using time-of-flight sequence, did not disclose any intracranial aneurysms. 3 D-CT angiography revealed left internal carotid-posterior communicating artery (IC-PC) aneurysm. Maximum intensity projection display of CT angiography demonstrated the neck and head portions of IC-PC aneurysm (size = 8 mm). Furthermore, 3 D-CT angiography was beneficial for anatomical evaluation of the aneurysm and the surrounding bony structures. The false negative 3 D-MRA of our patient was thought to result from flow-related artifacts, slow blood flow in the aneurysm, the surrounding noise and the localization of aneurysm. False negative findings of cerebral aneurysms occasionally occur on 3 D-MRA or 3 D-CT angiography, in comparison with digital subtraction angiography. Thus, we should pay more attention to assessment of 3 D-MRA and 3 D-CT angiography in patients who have high risks of cerebral aneurysms.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Carotid Artery Diseases / diagnosis*
  • Carotid Artery, Internal
  • Cerebral Angiography / methods*
  • False Positive Reactions
  • Female
  • Humans
  • Intracranial Aneurysm / diagnosis*
  • Magnetic Resonance Angiography / methods*
  • Tomography, X-Ray Computed / methods*