Abstract
To date, despite the increasing number of genomic tools, there is no repository of ordered human BAC clones that covers entire chromosomes. This project presents a resource of mapped large DNA fragments that span eight human chromosomes at approximately 1-Mb resolution. These DNA fragments are bacterial artificial chromosome (BAC) clones anchored to sequence tagged site (STS) markers. This clone collection, which currently contains 759 mapped clones, is useful in a wide range of applications from microarray-based gene mapping to identification of chromosomal mutations. In addition to the clones themselves, we describe a database, GenMapDB (http://genomics.med.upenn.edu/genmapdb), that contains information about each clone in our collection.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Chromosome Mapping
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Chromosomes, Bacterial*
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Databases, Factual*
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Humans
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In Situ Hybridization, Fluorescence
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Internet
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Nucleic Acid Hybridization
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Physical Chromosome Mapping / methods*
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Polymerase Chain Reaction
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Sequence Tagged Sites
Associated data
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GENBANK/AF188068
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GENBANK/AF188069
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GENBANK/AF188070
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GENBANK/AF188071
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GENBANK/AF188072
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GENBANK/AF188073
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GENBANK/AF188079
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GENBANK/AF188080
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GENBANK/AF188088
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GENBANK/AF188089
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GENBANK/AF188091
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GENBANK/AF188094
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GENBANK/AF188095
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GENBANK/AF188097