DOTS (Directly Observed Treatment Strategy) project in Mongolia, 1995

Int J Tuberc Lung Dis. 1999 Oct;3(10):886-90.

Abstract

Objective: To establish a tuberculosis (TB) control programme consistent with recommendations made by the WHO and the International Union Against Tuberculosis and Lung Disease (IUATLD) in a country where, as in control programmes of the former USSR, TB management previously relied on active case-finding with radiology and long-term monitoring and treatment of patients.

Design and methods: A pilot DOTS strategy (directly observed treatment, short course) project was implemented in Dornod Aimak, Eastern Mongolia During a 6-week period, individuals with chronic cough of > or =3 weeks were screened with sputum smear microscopy. Smear-positive patients received a supervised 6-month regimen (2SRHZ/4RH). Outcome was assessed with smear examination 2, 5, and 6 months after the initiation of treatment.

Results: Screening of 1241 symptomatic individuals identified 169 smear-positive TB cases (14%). Most of them (92%) were cured as demonstrated by documented sputum conversion. Five patients completed treatment, but were not available for follow-up smear examination, four patients died and four defaulted.

Conclusion: The DOTS strategy was successfully introduced in a former socialist model country, paving the way to national DOTS implementation in Mongolia. It may serve as an example for countries with a health care tradition similar to that of the Commonwealth of Independent States.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Communicable Disease Control / methods
  • Communicable Disease Control / organization & administration
  • Drug Therapy, Combination
  • Humans
  • Mass Screening / methods
  • Mass Screening / organization & administration
  • Mongolia
  • Mycobacterium tuberculosis / isolation & purification
  • Pilot Projects
  • Sputum / microbiology
  • Time Factors
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / microbiology
  • Tuberculosis, Pulmonary / prevention & control*
  • World Health Organization

Substances

  • Antitubercular Agents