Echocontrast-enhanced ultrasound of extracranial internal carotid artery high-grade stenosis and occlusion

Stroke. 1999 Nov;30(11):2302-6. doi: 10.1161/01.str.30.11.2302.

Abstract

Background and purpose: Proper assessment of extracranial internal carotid artery high-grade stenosis and occlusion by extracranial color-coded duplex sonography (ECCD) is occasionally made difficult by shadowing, an unfavorable insonation angle, low flow velocity or volume, or a deep insonation depth. In these cases, echocontrast could be helpful to quantify the degree of stenosis and to diagnose occlusion.

Methods: We investigated 17 arteries with poor precontrast investigation conditions and suspected high-grade stenosis or occlusion by contrast-enhanced ECCD.

Results: Compared with the precontrast scans, echocontrast allowed for significantly more segments to be evaluated by pulsed Doppler sonography (P<0.001) and for longer lumen segments to be displayed on color mode (P<0.001). Because it was now possible to place the sample volume right into the jet of the stenosis, the maximal flow velocity registered increased in all patients with stenosis.

Conclusions: Echocontrast-enhanced ECCD of the carotid arteries is helpful for stenosis classification in a small group of preselected patients with poor original examination conditions.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Analysis of Variance
  • Angiography, Digital Subtraction
  • Arteriosclerosis / diagnostic imaging
  • Blood Flow Velocity / physiology
  • Carotid Artery, Internal / diagnostic imaging*
  • Carotid Stenosis / classification
  • Carotid Stenosis / diagnostic imaging*
  • Contrast Media*
  • Female
  • Humans
  • Image Enhancement / methods
  • Ischemic Attack, Transient / diagnostic imaging
  • Magnetic Resonance Angiography
  • Male
  • Middle Aged
  • Prospective Studies
  • Stroke / diagnostic imaging
  • Systole
  • Tomography, X-Ray Computed
  • Ultrasonography, Doppler, Color
  • Ultrasonography, Doppler, Duplex
  • Ultrasonography, Doppler, Pulsed* / methods

Substances

  • Contrast Media