Mesenchymoma are growths made up for two or more mesenchyme derivatives that normally not joint in the same tumor, with the exception of the connective tissue which appears in all tumors of mesenchymal lineage. Benign mesenchymoma is a rare tumor more frequent in extremities and peri-renal area or, very rarely in head and neck territories, being the oropharynx the most encountered sitting in the latter place. The paper reports a clinical case of benign cervical mesenchymoma of a long course, more than 20 years, and big size, asymptomatic and diagnosed through fine needle biopsy. After total removal the histological examination showed a composite growth of extended areas of fibrous tissue associated to vessels and other zones of ripe fat tissue.