Seprafilm-induced peritoneal inflammation: a previously unknown complication. Report of a case

Dis Colon Rectum. 1999 Dec;42(12):1639-43. doi: 10.1007/BF02236221.

Abstract

Introduction: Various substances and agents have been evaluated to prevent postoperative adhesion formation. Recently a sodium hyaluronate-based bioresorbable membrane was introduced with promising clinical results. Its application was regarded as safe and efficient.

Methods: We present the first reported case of a severe inflammatory reaction to a bioresorbable membrane and give a review of the related literature.

Conclusion: Bioresorbable membranes are increasingly used by general surgeons and gynecologists to reduce postoperative adhesion formation. Bioresorbable membranes may produce extensive inflammatory reactions.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Absorbable Implants / adverse effects*
  • Aged
  • Biocompatible Materials / adverse effects*
  • Colectomy
  • Colitis, Ulcerative / surgery
  • Humans
  • Hyaluronic Acid / adverse effects*
  • Ileostomy
  • Male
  • Membranes, Artificial*
  • Peritonitis / etiology*
  • Postoperative Complications / prevention & control
  • Postoperative Complications / surgery
  • Rectum / surgery
  • Tissue Adhesions / prevention & control
  • Tissue Adhesions / surgery

Substances

  • Biocompatible Materials
  • Membranes, Artificial
  • Seprafilm
  • Hyaluronic Acid