[Cystoid macular edema and cytomegalovirus retinitis in AIDS patients treated with antiretroviral triple therapy]

J Fr Ophtalmol. 1999 Dec;22(10):1034-41.
[Article in French]

Abstract

Aim of the study: This study evaluated cystoid macular edema (CME) occurring during inactive cytomegalovirus (CMV) retinitis, in AIDS patients treated with highly active antiretroviral therapy (HAART) and without anti CMV treatment for 10 patients.

Patients and methods: 12 patients were followed over 24 months. Assessment was carried out on visual acuity, biomicroscopy, fundus photographs every month, angiography for each patient, CD4 cell count and plasmatic viral load.

Results: 7 patients presented CME in association with chronic uveitis, large CMV retinitis scars and posterior pole involvement.

Conclusion: CME is a new complication of CMV retinitis occurring in patients treated with HAART.

Publication types

  • English Abstract

MeSH terms

  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / virology
  • Acquired Immunodeficiency Syndrome / drug therapy*
  • Adult
  • Antiviral Agents / therapeutic use*
  • Cytomegalovirus Retinitis / complications*
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • HIV Infections / drug therapy*
  • HIV Protease Inhibitors / therapeutic use*
  • Humans
  • Macular Edema / etiology*
  • Male
  • Middle Aged
  • Reverse Transcriptase Inhibitors / therapeutic use*

Substances

  • Antiviral Agents
  • HIV Protease Inhibitors
  • Reverse Transcriptase Inhibitors