Clinical presentation of stage IIIA (N2) non-small cell lung cancer: role of multimodality therapy

Chest. 1999 Dec;116(6 Suppl):497S-499S. doi: 10.1378/chest.116.suppl_3.497s.

Abstract

Neoadjuvant chemotherapy before surgical resection of locally advanced non-small cell lung cancer (NSCLC) has been shown to improve survival compared with surgery alone in several randomized clinical trials. A case report is presented describing the use of paclitaxel and carboplatin in a multimodality regimen for a patient with stage IIIA N2 NSCLC. Studies are ongoing to determine the optimal type and timing of chemotherapy.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adenocarcinoma / secondary
  • Adenocarcinoma / therapy*
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents, Phytogenic / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carboplatin / administration & dosage
  • Carcinoma, Non-Small-Cell Lung / secondary
  • Carcinoma, Non-Small-Cell Lung / therapy*
  • Humans
  • Lung Neoplasms / therapy*
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoadjuvant Therapy*
  • Neoplasm Staging
  • Paclitaxel / administration & dosage
  • Pneumonectomy
  • Radiotherapy, Adjuvant
  • Time Factors

Substances

  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Carboplatin
  • Paclitaxel