Simvastatin reduces postischemic coronary dysfunction: ultrastructural and functional findings after acute administration

Microvasc Res. 2000 Jan;59(1):181-5. doi: 10.1006/mvre.1999.2190.

Authors

P Di Napoli¹, M Di Muzio, A Maggi, A A Taccardi, P Conti, A Barsotti

Affiliation

¹ Department of Cardiology, Casa di Cura Villa Pini, Italy.

PMID: 10625587
DOI: 10.1006/mvre.1999.2190

No abstract available

MeSH terms

Animals
Capillaries / drug effects
Capillaries / ultrastructure
Coronary Vessels / drug effects*
Coronary Vessels / pathology
Coronary Vessels / ultrastructure
Dose-Response Relationship, Drug
Heart / drug effects*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
In Vitro Techniques
Male
Microcirculation / drug effects*
Microcirculation / pathology
Microcirculation / ultrastructure
Microscopy, Electron
Mitochondria / drug effects
Mitochondria / ultrastructure
Myocardial Ischemia / drug therapy
Myocardium / pathology
Myocardium / ultrastructure*
Perfusion
Rats
Rats, Wistar
Reperfusion Injury / drug therapy
Reperfusion Injury / pathology
Simvastatin / administration & dosage*

Substances

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Simvastatin