[Abiotrophia related endocarditis: contribution of molecular biology]

Presse Med. 1999 Dec 11;28(39):2149-51.
[Article in French]

Abstract

Background: Former nutritionally-deficient (variant) streptococci were recently separated from other streptococci viridans to constitute a new Abiotrophia genus, subdivided into two species, Abiotrophia defectiva (ex-Streptococcus defectivus) and Abiotrophia adjacens (ex-Streptococcus adjacens).

Case report: A woman was admitted to the hospital because of purpura and fever. Vegetations were shown by trans-esophageal echocardiography. Although blood samples were positive within 24 hours, accurate identification of the morphologically and biochemically streptococcus-like bacteria that had grown remained impossible. Molecular biology technicals permitted to identify Abiotrophia defectiva, ex-Streptococcus defectivus.

Discussion: This new genus is important to be identified in clinical practice, because of the increased virulence of these bacteria, when compared with Streptococci viridans. They are also frequently penicillin-resistant. Molecular biology technicals allow precocious diagnosis, and make possible the improvement of the prognosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / microbiology*
  • Endocarditis, Bacterial / therapy
  • Female
  • Humans
  • Middle Aged
  • Molecular Biology
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / microbiology*
  • Streptococcal Infections / therapy
  • Streptococcus / classification
  • Terminology as Topic