Abstract
Phase-contrast x-ray computed tomography (CT) indicates the distribution of the refractive index and has potential to reveal the structures inside soft tissues without a contrast agent. With a synchrotron x-ray source, phase-contrast x-ray CT with a triple Laue-case x-ray interferometer clearly differentiated various human pathologic tissues in the cases of hepatocellular carcinoma with cirrhosis and metastatic colon carcinoma to the liver, and the images closely corresponded to those obtained with low-magnification optical microscopy.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Carcinoma, Hepatocellular / diagnostic imaging*
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Carcinoma, Hepatocellular / pathology
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Colonic Neoplasms / diagnostic imaging*
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Colonic Neoplasms / pathology
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Equipment Design
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Humans
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Liver / diagnostic imaging
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Liver / pathology
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Liver Cirrhosis / diagnostic imaging*
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Liver Cirrhosis / pathology
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Liver Neoplasms / diagnostic imaging*
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Liver Neoplasms / pathology
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Liver Neoplasms / secondary
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Microscopy
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Radiographic Image Enhancement*
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Refractometry
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Sensitivity and Specificity
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Synchrotrons*
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Tomography, X-Ray Computed / instrumentation*