Segmental hepatic vein thrombosis associated with heparin-induced thrombocytopenia II

Virchows Arch. 2000 Jan;436(1):88-91. doi: 10.1007/pl00008204.

Abstract

We report the case of a 55-year-old man who developed heparin-induced thrombocytopenia II after a vertebral fracture. Autopsy revealed segmental hepatic vein thrombosis of the right lobe with subacute congestion and an activation of hepatic stellate cells. This case shows that heparin-induced thrombocytopenia II is a possible cause of the Budd-Chiari syndrome.

Publication types

  • Case Reports

MeSH terms

  • Anticoagulants / adverse effects*
  • Biomarkers / analysis
  • Budd-Chiari Syndrome / etiology*
  • Budd-Chiari Syndrome / pathology
  • Heparin / adverse effects*
  • Hepatic Veins / pathology
  • Humans
  • Immunohistochemistry
  • Liver / blood supply
  • Liver / chemistry
  • Liver / drug effects
  • Liver / pathology*
  • Male
  • Middle Aged
  • Thrombocytopenia / chemically induced*

Substances

  • Anticoagulants
  • Biomarkers
  • Heparin