Alopecia areata-like hair loss in C3H/HeJ mice and DEBR rats can be reversed using topical diphencyprone

J Shapiro; J P Sundberg; R Bissonnette; K J McElwee; D I McLean; J M Carroll; R F Oliver; L Tang; H Lui

doi:10.1038/sj.jidsp.5640219

Alopecia areata-like hair loss in C3H/HeJ mice and DEBR rats can be reversed using topical diphencyprone

J Investig Dermatol Symp Proc. 1999 Dec;4(3):239. doi: 10.1038/sj.jidsp.5640219.

Authors

J Shapiro¹, J P Sundberg, R Bissonnette, K J McElwee, D I McLean, J M Carroll, R F Oliver, L Tang, H Lui

Affiliation

¹ Division of Dermatology, University of British Columbia, Vancouver, Canada.

PMID: 10674374
DOI: 10.1038/sj.jidsp.5640219

Abstract

This study demonstrates the ability to treat successfully alopecia areata-like hair loss in both mouse and rat models using topical immunotherapy with diphencyprone.

MeSH terms

Administration, Topical
Alopecia Areata / drug therapy*
Animals
Cyclopropanes / administration & dosage*
Mice
Rats

Substances

Cyclopropanes
diphenylcyclopropenone