Objective: To understand the of immuno-reactions of pediatrics patients with Mycoplasma pneumonia.
Methods: 90 patients suffered from M. pneumonia were administered and divided into three groups: mild group, severe group, and normal control group. T cell subset parameters, natural killer cell and the serumsoluble interleukin-2 recepter of all of above were determined.
Results: Data showed:CD4 decreased at both acute and recovery stage of M. pneumonia, while CD8 remarkably increased (t = 2.63, 66, 2.77, 3.36, P < 0.05). SIL-2R level of all patients also greatly increased (t = 5.26, 3.19, P < 0.01), especially in the serious group.
Conclusion: There are disturbances of cell-immune in M. pneumonia. The level of SIL-2R can serve as monitor on the degree of severeness of M. pneumonia. The incidence M. pneumonia appeared highest in the 10-14 year-old group.