Successful rescue by oral cholestyramine of a patient with methotrexate nephrotoxicity: nonrenal excretion of serum methotrexate

Med Pediatr Oncol. 2000 Mar;34(3):226-8. doi: 10.1002/(sici)1096-911x(200003)34:3<226::aid-mpo15>3.0.co;2-#.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anion Exchange Resins / administration & dosage
  • Anion Exchange Resins / therapeutic use*
  • Antimetabolites, Antineoplastic / adverse effects*
  • Antimetabolites, Antineoplastic / blood*
  • Antimetabolites, Antineoplastic / therapeutic use
  • Bone Neoplasms / blood
  • Bone Neoplasms / drug therapy
  • Child
  • Cholestyramine Resin / administration & dosage
  • Cholestyramine Resin / therapeutic use*
  • Humans
  • Kidney / drug effects*
  • Kidney / metabolism
  • Liver / drug effects*
  • Liver / metabolism
  • Male
  • Methotrexate / adverse effects*
  • Methotrexate / blood*
  • Methotrexate / therapeutic use
  • Osteosarcoma / blood
  • Osteosarcoma / drug therapy
  • Tibia
  • Time Factors
  • Treatment Outcome

Substances

  • Anion Exchange Resins
  • Antimetabolites, Antineoplastic
  • Cholestyramine Resin
  • Methotrexate