Simulated microgravity impairs vascular contractility: role of nitric oxide-dependent vasodilator mechanisms

Proc West Pharmacol Soc. 1999:42:5-7.

Authors

D S Sangha¹, N D Vaziri, Y Ding, S Han, N Alem, Y A Chen, R E Purdy

Collaborator

R E Purdy²

Affiliations

¹ Department of Pharmacology, College of Medicine, University of California-Irvine 92697-4625, USA.
² U CA, Irvine

PMID: 10697672

No abstract available

MeSH terms

Animals
Arteries / drug effects
Arteries / physiology
Endothelium, Vascular / physiology
Hindlimb Suspension / adverse effects
Hindlimb Suspension / physiology
Muscle Contraction / drug effects
Muscle, Smooth, Vascular / physiology*
Nitric Oxide / physiology*
Nitric Oxide Synthase / biosynthesis
Nitric Oxide Synthase / metabolism
Nitric Oxide Synthase Type III
Norepinephrine / pharmacology
Rats
Rats, Wistar
Up-Regulation / physiology
Vasoconstrictor Agents / pharmacology
Vasodilation / drug effects
Vasodilation / physiology*
Weightlessness Simulation / adverse effects*

Substances

Vasoconstrictor Agents
Nitric Oxide
Nitric Oxide Synthase
Nitric Oxide Synthase Type III
Nos3 protein, rat
Norepinephrine