Assignment of Pdnp2, the gene encoding phosphodiesterase I/nucleotide pyrophosphatase 2, to mouse chromosome 15D2

Cytogenet Cell Genet. 1999;87(3-4):172-4. doi: 10.1159/000015459.

Abstract

We have isolated cDNA and genomic DNA encoding mouse PDNP2 (PD-Ialpha). The mouse Pdnp2 cDNA contains a 2,589-nucleotide open reading frame encoding a polypeptide of 863 amino acids. The 5' region of the mouse Pdnp2 gene contains Sp1, Max1, HNF-3B, and AP1 putative transcription factor binding sites, without typical TATA or CAAT boxes. Fluorescence in situ hybridization showed that Pdnp2 is located at Chromosome 15D2, as expected based on mouse-human conserved regions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cloning, Molecular
  • Conserved Sequence / genetics
  • DNA, Complementary / genetics
  • Expressed Sequence Tags
  • Humans
  • In Situ Hybridization, Fluorescence
  • Mice
  • Molecular Sequence Data
  • Open Reading Frames / genetics
  • Physical Chromosome Mapping*
  • Promoter Regions, Genetic / genetics
  • Pyrophosphatases / genetics*
  • Response Elements / genetics

Substances

  • DNA, Complementary
  • Pyrophosphatases
  • nucleotide pyrophosphatase

Associated data

  • GENBANK/AF123542
  • GENBANK/AF128879